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Completed SDBTT Funded Research

Research:   

Functional and clinical analysis of the RASSFlA tumour suppressor gene in Childhood medulloblastoma

Team:

Dr Stephen Clifford, UNIVERSITY OF NEWCASTLE

   
Research:   

Identification of Novel Genes silenced through CpG Island Methylation in Pituitary Tumours using DNA Microarray Analysis

Team:

Dr Bill Farrell, UNIVERSITY OF KEELE

   
Research:   

The development of novel toxin cargo delivery systems for glioblastoma multiforme (GBM)

Team:

Professor John Darling, UNIVERSITY OF WOLVERHAMPTON

   
Research:   

Tracking delays in diagnosis of brain & spinal tumours

Team:

Dr David Walker, UNIVERSITY OF NOTTINGHAM

   
Research:   

Molecular characterisation of 12 differentialy expressed genes identified by microarray analysis in paediatric ependymoma

Team:

Dr Tracy Warr, INSTITUTE OF NEUROLOGY, LONDON

   
Research:   

Investigation of the functions of vascularendothellal growth factor-a and Interleukin-10 in brain tumours and the potential of these factors as prognostic markers

Team:

Dr John Greenman UNIVERSITY OF HULL

   
Research:   

An in depth study over time on the effect of child and parent factors in perceived quality of life of children treated for brain tumour

Team:

Dr Colin Kennedy, UNIVERSITY OF SOUTHAMPTON

   
Research:    Gene Therapy Strategies for the enhancement of Radiotherapy in Human Tumours
Team: Royal Marsden Hospital, Surrey
 
Research: NG2 and its relationship to Adult and Childhood Brain Tumours NG2 and its relationship to Adult and Childhood Brain Tumours
Team: St. Thomas Hospital, London
 
Research: DNA Study of Childhood Astrocytomas
Team: Institute of Neurology, London
 
Research: Identification of novel genes on chromosome 8q expressed in malignant astrocytoma in children and younger adults
Team: Institute of Neurology, Queen Square, London
Funding: SDBTT & BTUK
 
Research: Longitudinal study of MRI and Spectroscopy techniques in evaluation of the natural history of Low Grade Gliomas.
Team: Institute of Neurology, London
Funding: SDBTT Astrofund
 
Research: A new approach to the Localisation of genes involved in Paediatric Brain Tumours using comparative Genomic Hybridisation
Team: University of Sheffield Medical School
 
Research: Evaluation of the Dietary Additive Aspartame (‘Nutrasweet’) as a risk factor for central nervous system tumours
Team: Kings College, London
 
Research: Development of a spheroid model to study the pathogenesis and regulation of gliomas cell death
Team: Western General Hospital, Edinburgh
 
Research: Comparison of quality of survival between children randomly allocated to different treatments for medulloblastoma
Team: Southampton General Hospital
 
Research: An indepth study over time on the effect of child and parent factors on the perceived quality of life of children treated for brain tumour or for leukaemia
Team: Southampton General Hospital
Funding: SDBTT & BTUK
 
Research: Molecular genetic analysis of medulloblastomas
Team: Addenbrooke's Hospital, Cambridge
 
Research: Cathepsin S expression in astrocytomas – its invasion and potential value as a therapeutic target.
Team: Queens Universtity of Belfast
 
Research: Genome-wide allelotyping of medulloblstomas
Team: University of Newcastle
Funding: SDBTT & Charlie’s Challenge
 
Research: Citrus Flavonoids – a Role in brain tumour therapy
Team: University of Portsmouth
Funding: SDBTT, Luke Frost Games, BTUK, & Charlie’s Challenge
 
Research: The PMS2 gene and its role in childhood brain tumours
Team: Dr Eamonn Sheridan, UNIVERSITY OF LEEDS
Funding: SDBTT
     
Research: The molecular basis of supratentorial primitive neuroectrodermal tumour (sPNET)  
Team: Dr David Ellison, UNIVERSITY OF NEWCASTLE  
Funding: SDBTT, BBTA & Luke Frost Games  
     
Research: Multimodality imaging of low-grade gliomas: Study natural history and predicting malignant transformation  
Team: Dr Jeremy Rees, INSTITUTE OF NEUROLOGY, LONDON  
Funding: SDBTT Astrofund  
     
     
     


 

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